摘要
对64例慢性肺源性心脏病患者血清过氧化脂质(LPO)及超氧化物歧化酶(SOD)含量的检测观察。结果显示慢性肺心病患者LPO及SOD水平高于对照组,差异有显著性(P<0.01);肺心病急性发作期又高于缓解期.差异有显著性(P<0.05),提示在慢性缺氧及感染状态下脂质过氧化反应增强,在肺心病的病理发展过程中可能起到一定促进作用。氧自由基(OFR)对肺组织细胞损伤的不同程度反映了肺心病病情变化的一定阶段。
Detection on the quantity of lipid peroxide(LPO ) and superoxide dismutase (SOD) in sorum of 64 cases chronic pulmonary heart disease indicated that the level of LPO and SOD are higher than the control group (P <0. 01 ) and the level of LPO and SOD in atack stase of disease are higher that in remission stage (P <0. 05). It showed that LPO reaction in the state of chromic deoxygen and infection may increaesed aggravating the pathologic change, The different degree of injured lung tissue cells by oxygen free radIcal reflected the clinical development of pulmonary heart disease.
出处
《贵州医药》
CAS
1996年第2期70-71,共2页
Guizhou Medical Journal
关键词
肺心病
过氧化脂质
超氧化物歧化酶
氧自由基
Oxygen free radical, Lipid peroxide, Superoxide dismutase, pulmonary heart disease