雌性大鼠去势后股骨生物力学变化

BIOMECHANICAL EFFECTS IF BILATERAL OVARIECTOMIESON FEMORA IN RATS

３月龄ＳＤ大鼠去势６个月后，采用三点弯曲试验描记肢骨的负荷－变形曲线，计算肢骨最大负荷和致断应力，与对照组比较。反映股骨组成材料力学性能的致断应力，去势后显著降低。反映整根股骨力学性能的最大负荷，去势后虽有减小，但无显著性差异。结果表明：雌性大鼠去势后股骨组成材料的力学性能受到显著损害，而整根股骨的力学性能．因几何形状的优化，无明显变化。

Three-point bending test was carried out to determine the femoral load-deformntion curve when the SD rats'bilateral ovariectomies were performed six months ago. Compared to stham-operated control rats,the breaking stress indicating the biomechanical propery of femoral material was significantly decreased,the maximum lood reflecting was slightly diminished.The results show:(1)the biomechanical property of ovariectomized rats femora material was significanthy impaired.(2)attributed to the superior change of geometric configuration,the biomechanical quality of femoral diaphysis has no apparently change.