梗阻性黄疸患者梗阻解除前后血清相关元素及免疫球蛋白含量测定

Studies on the interrelated elements content and immune globulin in serum before and after operation for patients with onbstructive jaundice

用火焰原子吸收光谱法及彩色免疫单扩散定量检测板法分别对３５例梗阻性黄疸患者梗阻解除前后血清铜锌铁含量及血清ＩｇＧ、ＩｇＡ、ＩｇＭ含量进行了测定。结果表明，血清铜水平梗阻性黄疸梗阻解除后不同时间明显低于梗阻解除术前（Ｐ＜０．００１）。血清锌水平梗阻解除术后显著高于术前，以梗阻解除术后４、７、２１天显著（Ｐ＜０．０１）。血清铁水平梗阻解除术后与术前比较仍随时间推移而升高明显，同样以４、７、２１天为最显著（Ｐ＜０．００１）。血清ＩｇＧ、ＩｇＡ、ＩｇＭ含量随梗阻解除术后时间变化与术前比较也有明显下降趋势，以梗阻解除术后３、４、７、２１天为最显著（Ｐ＜０．００１）。本组病人梗阻解除前后血清铜锌铁水平与同时间血清ＩｇＧ、ＩｇＡ、ＩｇＭ含量比较，其中血清铜水平与血清ＩｇＧ含量有良好的相关性（ｒ＝０．９Ｐ＜０．０１）。研究结果可作为梗阻性黄疸系统治疗中的动态观察指标，对梗阻性黄痘的综合治疗有重要意义。

This paper The level of Cu,Zn,Fe and IgG,IgA,IgM in serum before and after operation were detected by flame aiomicabsorption method and immunodiffusion with immunoquantitation in 35 case of obstructive jaundice patients which be verified byclinlc and oepration.The result shouted that:the level of Cu in serum before operation were significantly higher than that after op-eration(P<0. 001).The level of Zn,Fe in serum before operation were noticely lower than that after operation(P<0. 001).The level of IgG,IgA,IgM in serum before operation were significantly higher than that after operation(P<0. 001 ).This index which be dynamics,observed,has a important role in treatment and judged the prognosisfor obstructive jaundice patients.