合成α-蒎烯-马来酸酐加成物的新工艺研究(英文)

Study on a new technology of synthesizing α-pinene-maleic anhydride adduct

在DLB催化下,α-蒎烯经异构同时和马来酸酐发生D ie ls-A lder反应合成1-异丙基-4-甲基二环[2.2.2]-5-辛烯-2,3-二酸酐(TM A)。首次运用正交设计法研究了合成TM A的主要影响因素,TM A的收率达88.2%,纯度达92.7%,并明显缩短了反应时间。利用IR、TLC、GC、GC-M S-DS等手段对TM A进行了分析和表征。

1-Isopropyl-4-methyl-bicyclo [ 2. 2. 2]-oct-5-ene-2, 3-dicarboxylic anhydride （α-terpinene-maleic anhydride adduct, TMA） was prepared by isomerization of a-pinene and Diels-Alder reaction with maleic anhydride using DLB as catalyst. Influence factors were studied and the optimum conditions were obtained by orthogonal experimental design. The yield of TMA was 88.2% and the purity was up to 92.2%. TMA was analyzed and characterized by IR,TLC,GC and GC-MS-DS methods.