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盐皮质激素受体与内耳

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摘要 生理条件下盐皮质激素(醛固酮)主要通过盐皮质激素受体(mineralocortieoid receptor,MR)发挥作用。MR属于类固醇,甲状腺,维生素A配体依赖的转录因子受体超家族(steroid/thyroid/retinoid receptor supedamily of ligand—dependent transcription factors)的一员。体内除了肾脏、结肠、唾液腺这些经典的靶组织以外还存在多处MR作用的靶组织。本文拟综述MR的结构特点、作用方式及其与内耳组织的关系。
作者 李琦 黄德亮
出处 《中华耳科学杂志》 CSCD 2006年第1期70-71,共2页 Chinese Journal of Otology
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