肝硬化并门脉高压性胃病的临床研究

Clinical analysis of portal hypertensive gastropathy in patients with hepatocirrhosis

目的:探讨肝硬化并门脉高压性胃病(PHG)的临床特点及其与肝功分级、食管静脉曲张的关系．方法:对208例肝硬化患者进行常规胃镜检查,并对其并发PHG情况进行回顾性分析．结果:208例肝硬化患者中,食管静脉曲张178 例(85．6％),PHG发生率为38．0％(79例)．随肝功能Child-Pugh分级级别增加,PHG发病率及严重程度呈上升趋势(P<0．01);而随着食管静脉曲张严重程度上升,PHG发病率亦有上升 (P<0．05);原无PHG的19例患者硬化剂治疗后有4例(21．1％)出现PHG．结论:肝硬化患者PHG发病率随肝功能分级及食管静脉曲张严重程度的增加而上升．

AIM： To discuss the clinical characteristics of portal hypertensive gastropathy （PHG） in patients with hepatocirrhosis and its relations with liver function and varicosity of esophagus. METHODS： Gastric endoscopy was performed in 208 inpatients with hepatocirrhosis and the incidence rate of PHG was retrospectively analyzed. RESULTS： Of all the 208 patients, 178（85.6%） had varicosity of esophagus and the incidence rate of PHG was 38.0%（79/208）. The incidence rate of PHG was increased with the increased grade of live function （2 = 22.151, P 〈 0.01） and esophageal varicosity （2 = 16.656, P 〈 0.05）. After endoscopic injection sclerotherapy in 19 patients, PHG appeared in 4 （21.1%）. CONCLUSION： The incidence rate of PHG is increasing with the increased grade of live function and the severity of esophageal varicosity.