柔红霉素中间代谢产物ε－紫红霉酮的累积

ACCUMULATION OF ε-RHODOMYCINONE IN DAUNOMYCIN FERMENTATION LIQUID

由柔红霉素产生菌──天蓝淡红放线菌正定变种诱变得到的７８－１５２变株在以糯米粉、蔗糖等为碳源的培养基Ａ中产生柔红霉素，但在以甘油为主要碳源的培养基Ｂ中却大量累积ε－紫红霉酮。而它的亲株却没有这一特性。因此７８－１５２菌株为一生化变株。

Actinomyces coeruleorubidus var. zhengdingensis[HB1482] produces daunomycin, but its variant strain 78-152 produces ε-rhodomycinone in the medium containing glycerol as the main carbon source.