摘要
用二阶导数分光光度法测定布洛芬溶液的经皮释药量,可消除鼠皮溶出物的干扰。方法简便、快速、准确。布洛芬的平均回收率为99.94%,RSD=0.185%。
Second order derivative spectrophotometry of transdermic permeability of ibuprofen liquid could eliminate the disturbance of dissolution of mouse's skin.This method was simple,rapid and precise.The average recovery of ibuprofen was 99.94%,RSD=0.185%.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1996年第6期262-264,共3页
Chinese Journal of Pharmaceuticals
关键词
布洛芬
二阶导数
分光光度法
经皮渗透
ibuprofen,second order derivative spectrophotometry,transdermic permeability