普卡霉素产生菌SIPI91－81的分类与鉴定

CLASSIFICATION AND IDENTIFICATION OF MITHRAMYCIN-PRODUCING STRAIN SIPI 91-81

从上海郊区土壤中分离到一株链霉菌，编号ＳＩＰＩ９１－８１，其代谢产物具有抗肿瘤活性。经鉴别该活性物质与普卡霉素为同一物质。该菌株在形态培养特征和生理生化特征上与已知的暗黑橄榄链霉菌相似，但又有一定的差别，故定名为暗黑橄榄链霉菌上海变种（ＳｔｒｅｐｔｏｍｙｃｅｓａｔｒｏｏｌｉｖａｃｅｕｓｓｈａｎｇｈａｉｅｎｓｉｓＳＩＰＩ９１－８１）。

The strain SIPI 91-81 isolated from soil samples collected in suburbs of Shanghai has been found to produce antitumor compound identical with mithramycin.This producing strain is similar to known Streptomyces atroolivaceus mithramycin-producing strain 11294, but still has some differences in cultural and physiological characteristics.Therefore, it is named Streptomyces atroolivaceus shanghaiensis SIPI 91-81.