穿透性角膜移植术128例临床分析

A clinical analysis on 128 cases of penetrating keratoplasty

目的评价穿透性角膜移植术治疗角膜疾病的疗效。方法对128例(128眼)角膜混浊病人行穿透性角膜移植术,于术后1月、3月、6月、12月、24月观察角膜的透明情况以及并发症。结果穿透性角膜移植术后1月128眼中82眼透明(64.1%),术后6月90眼中69眼透明(76.7%),术后12月84眼中53眼透明(63.1%),术后24月43眼中27眼透明(62.8%)。以此同时,患者的视力均有不同程度的增加,术后1月角膜透明82眼中有67眼矫正视力大于0.1(82%),术后3月63眼中有59眼矫正视力大于0.1(94%)同,术后6月69眼中有66眼矫正视力大于0.1(96%)。结论穿透性角膜移植术是治疗因角膜病致盲患者的重要手段,排斥反应是术后主要并发症,三联手术安全有效。

Objective To evaluate the therapeutic effect of PKP on corneal disease. Methods PKP was done on 128 patients with corneal disease and then followed up on months 1, 3, 6, 12 and 24. Clarity of cornea and complications were recorded. Results Grafts were transparent in 82 of 128 eyes month 1（64.1%）, in 69 of 90 eyes on months 6（76.7%）, in 53 of 84 eyes on months 12（63.1%）, in 27 of 43 eyes on months 24（62. 8%）, after PKP. At the same time. Corrected vision were improved on different degrees. Vision of patients with transparent grafts were more than 0. 1 in 67 of 82 patients（82%） on month l, in 59 of 63 patients（94%） on months 3, in 66 of 69 patients（96%） on months 6. Conclusions PKP is an important method to therapy the corneal disease. Rejection was the major complication. PKP combined with extra capsular cataract extraction and IOL implantation is effective and safe.