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小剂量阿斯匹林预防妊高征疗效研究 被引量:1

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摘要 采用前瞻性随机临床研究有妊高征高危因素孕20~38W 孕妇104名,随机分为2组。服药组在孕30W 后予阿斯匹林50mg/d,连服3~5周。结果:妊高征孕妇血浆 TXB_2及 TXB_2/6—Ke-toPGF_(1α)明显高于未发生妊高征者(P<0.01)。服药组妊高征显著低于对照组(P<0.01),血浆 TXB_2及 TXB_2/6—KetoPGF_(1α)明显下降(P<0.05)。说明:血浆 TXB_2及 TXB_2/6—KetoPGF_(1α)升高者妊高征发病率明显增加;阿斯匹林能降低血浆 TXB_2浓度和调整 TXB_2/6—KetoPGF_(1α)值,可预防妊高征发生。
出处 《苏州医学院学报》 1996年第3期551-553,共3页 Acta Academiae Medicinae Suzhou
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