复方磺胺嘧啶银混悬液中两组分含量的同时快速测定法

Simultaneously rapid determination of two components in compound sulfadiazine argenticum suspensions

本文利用偏最小二乘──紫外分光光度法同时测定复方磺胺嘧啶银混悬液中磺胺嘧啶银和醋酸洗必泰的含量，平均回收率分别为：１００．４８±０．１８％和１００．４９±０．３０％（置信度９５％）。实测三批样品，结果准确可靠。测定波长２５４ｎｍ，为４４７三、讨论（一）采用常规最小二乘法［３］处理同样数据，所得结果见表１，由此可知，偏最小二法比常规最小二乘法优越，是一种适用于批量分析和结果准确可靠的方法，而且节省时间和实验试剂，对仪器的要求低，重复性好。（二）处方中醋酸洗必泰的含量相对于磺胺嘧啶银少得多，为了克服低组分含量测定误差大，采用添加法，可以减少测量和计算误差。

Two components of sulfudiazine argenticum and chlorhexidini acetas in compound sulfadiazine argenticum suspensions are determined simultaneously by using PLS method in this paper. The average recovery ratio of two components are 100.48±0.18%and 100.49±0.30% respectively(confidence 95%). Three batches of sample were determined and the results were accurate and rehiable.