摘要
本文对52例慢性肾功能不全不同临床分期即肾功能正常期、氮质血症期、尿毒症期患者及正常人血清中可溶性白细胞介素-2受体(sIL-2R)水平进行了检测,结果分别为213±46.5,33.3±81,8,568±198.7,197±44.2(u/ml)。表明慢性:肾功能不全肾功能正常期患者血清中sIL-2R与正常人血清中sIL-2R水平无明显差异;而氨质血症期与尿毒症期患者sIL-2R均明显高于正常人(P<0.01),且sIL-2R水平与血中尿素氮及肌酐含量呈一定的平行关系。提示sIL-2R测定,对慢性肾功能不全患者的病情监测、临床分期、药物治疗效果及预后判断等都有一定的参考价值。
The level of the soluble interleukin 2 receptor (sIL-2R)in the serum of 52 patientswith chronic renahnsumciency was tested.THe results showed that.the level of sIL-一2R in serum ofthe patients with chronic renal insufficiency in the phases of azotemia and uremia was much higherthan that of sIL-2R of the control(P<0.01),and parallel relationship between the levels of slL-2R and of BUN and creatinine of the patients was presented.We suggest that the measurement of lev-el of sIL-2R has great referential value for judgment on the developing conditions of disease,clinicalphase and drug therapeutic effect.
出处
《白求恩医科大学学报》
CSCD
1996年第3期270-271,共2页
Journal of Norman Bethune University of Medical Science
关键词
慢性
肾功能不全
白细胞介素
chronic renal insufficiency
sIL-2R
azotemia
uremia