紫外线照射充氧自血回输疗法对细胞遗传学的影响

Enects of oxygenated autoinfusion therapy with UV-irradiation on cytogenetics

作者对采用紫外线照射充氧自血回输疗法（ＵｌｔｒａｖｉｏｌｅｔＢｌｏｏｄＩｒｒａｄｉａｔｉｏｎ，ＵＢＩ）治疗的１０名患不同疾病的患者，在ＵＢＩ治疗前、治疗后（第５和第１０次）进行外周血淋巴细胞微核及染色体畸变的检测。结果发现，随着治疗次数增加，染色体畸变率略有增加趋势，但未超出正常范围（＜１％）；淋巴细胞微核率随治疗次数的增加也有增高趋势，但均在正常值（０～２‰）范围内。提示：人体少量自血经ＵＢＩ处理后再回输体内，对细胞遗传学无明显不良影响。

The present study was designed to determine the micronucleus of human peripheryblood lymphocytes and the chromsomal aberration of ten patients with cardiovascular and cerebrovas-cular diseases before treatment and after treatment(five and ten times)using oxygenated autoinfusiontherapy with UV-irradiation,The results showed that the chromosomal aberration rates had an in-creasing tendency with the increase of treating times,but the rates were lower(<1%);the lynlpho-cyte micronucleus retes were 0.28‰0.44‰and 0.86‰,respectively,and the rates also had an in-creasing tendency with the increase of treating times,but they all were in normal range. These resultssuggest that a small amount of human blood treated by UV-irradiation again performs the autotrans-fusion,wihich does not possess effect on cytogentics,and the therapy is,afe and reliable.