心脉通贴剂中冰片的透皮吸收实验研究

Experimentalstudyon transdermal absorbability of Borneol in Xinmaitong Plaster

目的:研究心脉通贴剂的透皮吸收状况;方法:以小鼠为实验对象,测试心脉通贴剂对鼠皮的透皮吸收率;结果:3个批次的样品之间对比,无统计学差异(P>0.05),且在实验后6h^8h,透皮吸收率可达到13%左右。结论:本贴剂中的冰片在人体表皮温度条件下透皮吸收效果较好,吸收率稳定。

Objective： To research transdermal absorbability of Xinmaitong Plaster. Methods： Transdermal absorbability of Xinmaitong Piaster was tested using the mice as experimental objects. Results： There were no statistic difference among transdermal absorbability of Borneol of three batchs. After 6 - 8 hours, the rate of skin absorbability was up to 13%, （ P 〉 0.05） Conclusion： The effects of Transdermal absorbability of Borneol in Xinmaitong Plaster is better at human skin temperature and the absorbability is stbale.