复方黄精对小鼠耐缺氧及抗疲劳能力的影响

Effects of the compound Polygonatum on anti-hypoxia capacity and anti-tiredness in mice

[目的]观察复方黄精对小鼠耐缺氧能力和抗疲劳能力的影响.[方法]分别灌胃给予4,2 g/kg复方黄精后,采用常压耐缺氧、负重游泳及转棒等实验方法,观察小鼠的缺氧存活时间、负重游泳存活时间及转棒耐力时间.[结果]复方黄精大剂量组小鼠缺氧存活时间及负重游泳存活时间均明显延长,复方黄精大、小剂量组小鼠的转棒耐力时间亦明显延长.[结论]复方黄精具有提高小鼠耐缺氧及抗疲劳能力的作用.

OBJECTIVE To study the effects of the compound Polygonatum on anti-hypoxia capacity and anti-tiredness in mice. METHODS The mice were observed by ordinary pressure hypoxia, loaded swimming and rotational stick to measure the survival time and endurance time after being given 2, 4 g/kg compound Polygonatum. RESULTS The survival time under the condition of ordinary pressure hypoxia and the loadling swimming of high dosage group of compound Polygonatum were prolonged, and the endurance time of rotational stick of low and high dosage groups of compound Polygonatum was prolonged, respectively. CONCLUSlON The compound Polygonatum has anti-hypoxia cpacity and anti-tiredness effects in mice.