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Synthesis of Novel Nucleoside Analogues Based on 1,3-Dihydrobenzo[c]furan Core 被引量:1

Synthesis of Novel Nucleoside Analogues Based on 1,3-Dihydrobenzo[c]furan Core
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摘要 A novel efficient synthetic route to 1,3-dihydrobenzo[c]furan glycone was developed and the corresponding 5-fluoro, 5-iodo uracil and guanosine derivatives, the aromatic analogues of the well known antiviral 2',3'-dideoxy-2',3'-dihydronucleosides (d4N), were synthesized. A novel efficient synthetic route to 1,3-dihydrobenzo[c]furan glycone was developed and the corresponding 5-fluoro, 5-iodo uracil and guanosine derivatives, the aromatic analogues of the well known antiviral 2',3'-dideoxy-2',3'-dihydronucleosides (d4N), were synthesized.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2006年第4期504-508,共5页 中国化学(英文版)
关键词 NUCLEOSIDE benzo[c]furan ANTIVIRAL nucleoside, benzo[c]furan, antiviral
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