纳米粒子标记DNA探针在电化学DNA生物传感器中的应用

The applications of nanoparticles tagging DNA probe in electrochemical DNA biosensors

介绍了纳米电化学DNA生物传感器的基本概念和分类,并介绍了用于DNA标记的纳米粒子的六种类型及其三大检测方法,在此基础上对纳米电化学DNA生物传感器在基因检测、疾病诊断、DNA检测等方面的最新进展进行了综述与讨论。

Much attention has been drawn to nanoparticles in electrochemical deoxyribonucleic acid （DNA） biosensors due to the advantage of enhancing the sensitivity of the biosensors. Nanoparticle tagging DNA probe,which combines of nano- technology, gene project and DNA detection, is the focus of recent research field. The principle and classification, labelled methods and principle of detection of nanoparticle tagging DNA probe are introduced. The applications of nanoparticles tagging DNA probe in electrochemical DNA biosensors arc reviewed.