1PINTO LA,BERZOFSKY JA,FOWKE KR,et al.HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients[J].AIDS,1999,13(15):2003 -2012.
2GAHERY-SEGARD H,PIALOUX G,CHARMETEAU B,et al.Multiepitopic B and T-cell responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine[J].J Virol,2000,74 (4):1694-1703.
3AN LL,RODRIGUEZ F,HARKINS S,et al.Quantitative and qualitative analyses of the immune responses induced by a multivalent minigene DNA vaccine[J].Vaccine,2000,18(20):2132.
5HANKE T,NEUMANN VC,BLANCHARD TK,et al.Effective induction of HIV-specific CTL by multi-epitope using gene gun in a combined vaccination regime[J].Vaccine,1999,17 (6):589.
6LIVINGSTON BD,CRIMI C,GREY H,et al.The hepatitis B virus-specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection[J].J Immunol,1997,159(3):1383 -1392.
7SERWOLD T,SHASTRI N.Specific proteolytic cleavages limit the diversity of the pool of peptides available to MHC Class Ⅰ molecules in living cells[J].J Immunol,1999,162 (8):4712.
8GILEADI U,GALLIMORE A,VAN DER BRUGGEN P,et al.Effect of epitope flanking residues on the presentation of N-erminal cytotoxic T lymphocyte epitopes[J].Eur J Immunol,1999,29 (7):2213 -2222.
9LININGSTON B,CRIMI C,NEWMAN M,et al.A rational strategy to design multi-epitope immunogens based on multiple Th lymphocyte epitopes[J].J Immunol,2002,168 (11):5499.
10CHOU KC.Prediction of tight turns and their types in proteins[J].Anal Biochem,2000,286 (1):1 -16.
3White AP, Collinson SK, Banser PA, et al. Salmonella enteritidis fimbriae displaying a heterologous epitope reveal a uniquely flexible structure and assembly mechanism [J ]. Journal of Molecular Biology, 2000, 296(2) : 361 - 372.
4Bauer H, Darji A, Chakraborty T, et al. Salmonella - mediated oral DNA vaccination using stabilized eukaryotic expression plasmids [J]. Gene Therapy, 2005, 12(4) : 364 - 372.
5Heithoff DM, Badie G, Julio SM, et al. In vivo - selected mutations in methyl- directed mismatch repair suppress the virulence attenuation of Salmonella dam mutant strains following intraperitoneal, but not oral, infection of Naive Mice[J]. Journal of Bacteriology, 2007, 189(13) :4708 - 4717.
6Heithoff DM, Enioutina EY, Daynes RA, et al. Salmonella DNA adenine methylase mutants confer cross- protective immunity [J ]. Infection and Immunity, 2001,69(11) : 6725 - 6730.
