中药和化学抗球虫药对兔球虫病的疗效对比试验

COMPARATIVE STUDIES ON THE EFFICACY OF CHINESE TRADITIONAL MEDICINE AND CHEMICAL MEDICINE AGAINST RABBIT COCCIDIOSIS

目的为比较中药和化学抗球虫药对兔球虫病的疗效。方法50只家兔随机均分为5组，Ⅰ组为无感染不用药空白对照组，Ⅱ-Ⅴ组各兔均感染，Ⅱ组为不用药对照组，Ⅲ组为中药组，Ⅳ组为地克珠利组，Ⅴ组为氯笨胍组，用药组饲喂含药饲料3天，兔人工感染混合球虫卵囊1×10^5个，观察效果。结果中药组与地克珠利组和氯苯胍组的抗球虫指数（ACI）分别为195、186和158，说明中药的抗球虫效果明显优于化学药物，两种化学药物中，地克珠利仍属高效抗球虫药，但氯苯胍的ACI仅为158，为低效抗球虫药；Ⅲ组家兔平均增重210．4g，经t检验，与Ⅰ组、Ⅳ组比较差异显著（P〈0．05），与Ⅱ组、Ⅴ组比较差异极显著（P〈0．01）。结论本试验表明，中药对家兔球虫病有防治作用，并有促进家兔生长的作用。

In order to compare the efficacy of Chinese traditional medicine and chemical medicine against rabbit coccidiosis. Rabbits（ n = 50） were randomly grouped in uninfected and unmedicated control（ Ⅰ ）, infected and unmedicated control（ Ⅱ ）, Chinese traditional medicine-treated（ Ⅲ ） , Diclazuril-treated （Ⅳ） and Robenidine- treated（ Ⅴ ） group. Group Ⅲ ,Ⅳ and Ⅴ were artificially infected with rabbit coccidian occysts （1 ×10^5） after fed with drugs for three days. The results of the experiment indicated that the ACI of the Chinese traditional medicine. Diclazuril and Robenidine were 195, 186 and 158 respectively. This means the efficacy against rabbits coccidiosis of Chinese traditional medicines more excellent than that of chemical Diclazuril, which is still a high efficacy coccidiostat. But Robenidine only has low efficacy against coccidiosis. The average body weight in group m increased by 210.4 gram as compared with that in group Ⅰ and Ⅳ （P 〈 0.05 ） , as compared with that in group Ⅱ and Ⅴ was significant different（P 〈0.01 ）. It could draw a conclusion that the Chinese traditional medicine had the effect of prevention and treatment of rabbit coccidiosis and improved the growth of rabbits.