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利培酮在双相障碍中的临床应用 被引量:4

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摘要 非典型抗精神病药利培酮通过多巴胺(D2)受体和5-羟色胺(5-HT2)受体的平衡拮抗作用,在各型精神分裂症的治疗中表现出了较好的疗效,且不良反应轻微。近年来,随着临床应用及研究的深入,发现该药物在其他精神疾病的应用中,也取得了较好的疗效。目前利培酮、奥氮平、奎硫平、齐拉西酮、阿立哌唑等非典型抗精神病药已被美国FDA批准用于治疗双相障碍如躁狂发作等亚型,现将其中利培酮在双相障碍中的临床研究和应用情况作一综述。
作者 陈涵 黄继忠
出处 《上海精神医学》 2006年第1期47-50,共4页 Shanghai Archives of Psychiatry
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