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A-NK细胞联合IL-2,IL-12在肿瘤免疫治疗中的作用 被引量:1

The Function on Tumor Immunotherapy with A-NK Cells Combined with IL-2 and IL-12
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摘要 本文对A-NK细胞联合IL-2和IL-12在抗肿瘤免疫治疗中的作用进行了论述。强调联合应用可高效激活A-NK细胞,提高对肿瘤细胞的杀伤活性。减少IL-2和IL-12的用量及副作用,提高疗效。 This article talks about the function on tumor immunotherapy with A - NK cells combined with IL - 2 and IL - 12. It stresses upon the combined utilization may activate A - NK cells with higher effectiveness and improve the killing activation for the tuner cells. It may decrease the usage and toxic effect of the IL - 2 and IL- 12, and also raise the treatment effect.
出处 《生物磁学》 CAS 2006年第1期79-80,共2页 Biomagnetism
关键词 A-NK细胞 肿瘤免疫治疗 联合应用 A- NK cells Tumor immunotherapy Combined Utilization
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参考文献13

  • 1Triozzi PL,Aidrich W,Kim J,et al.Biologic effects of the adoptive transfer of cells depleted of monocytes with L-phenylalanine methyl ester[J].Immunopharmacology,1994,28(1):37
  • 2Kitson RP,Ohashi M,Brunson KW,et al.Flavone acetic acid enhances accumulation of IL-2 activated NK cells within established metastases[J].In Vivo,1998,12(6):593
  • 3Melder RJ,Whiteside TL,Vujanovic NL,et al.A new approach to generating antitumor effectors for adoptive immunotherapy using human adherent lymphokine-actived killer cells[J].Cancer Res,1988,48(12):3461
  • 4Munari L,Silvani A,Passerini CG,et al.Adoptive immunotherapy with adherent lymphokine-activated killer (A-LAK) cells in glioblastoma multiforme[J].J Neurosurg Sci,1990,34(3-4):283
  • 5Hagenaars M,Ensink NG,Koelemi JR,et al.Regional administration of natural killer cells in a rat hepatic metastasis model results in better tumor infiltration and anti-tumor response than systemic administration[J].Int J Cancer,1998,75(2):233
  • 6Lister J,Rybka WB,Donnenberg AD,et al.Autologous peripheral blood stem cell transplantation and adoptive immunotherapy with activated natural killer cells in the immediate posttransplant period[J].Clin Cancer Res,1995,1(6):607
  • 7Wigginton JM,Komschlies KL,Back TC,et al.Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma[J].J Natl Cancer Inst,1996,88(1):38
  • 8郑晓东,田志刚.人类NK细胞亚群的分类及意义[J].中国肿瘤生物治疗杂志,2002,9(2):140-143. 被引量:3
  • 9王志华,申宝忠,史历.IL-4增强IL-2活化的A-NK细胞对人直肠癌CC95的抗肿瘤作用[J].世界华人消化杂志,2003,11(9):1375-1377. 被引量:3
  • 10Endsley JJ,Endsley MA,Estes DM.Bovine natural Killer cells acquire cytotoxic/effector activity following activation with IL-12/13 and reduce Mycobacterium bovis BCG in infected macrophages[J].J Leukoc Biol,2005,11(7):1-2

二级参考文献18

  • 1Lister J, Rybka WB, Donnenberg AD, et al. Autologous peripheral blood stem cell transplantation and adoptive immunotherapy with activated natural killer cells in the immediate posttransplant period. Clinical Cancer Research, 1995;1(6):607
  • 2Triozzi PL, Aldrich W, Kim J, et al. Biologic effects of the adoptive transfer of cells depleted of monocytes with L-phenylalanine methyl ester. Immunopharmacology, 1994;28(1):39
  • 3Kambe N, Kambe M, Chang HW et al. An improved procedure for the development of human mast cells from dispersed fetal liver cells in serurn-free culture medium. J Immunol Methods,2000;240:101
  • 4Lamont AG, Adorini L. IL-12: a key cytoline in immune regulation.Immunology Today 1996; 17(5) :214
  • 5Vujanovic NL, Yasumura S, Hirabayashi H, et al. Antitumnor activities of subsets of human IL-2 activated natural killer cells in solid tissues. J Immunol, 1995;154(1): 281
  • 6张彩,田志刚.粘附NK细胞的免疫学特性及其抗癌效应[J].国外医学(肿瘤学分册),1997,24(3):144-146. 被引量:10
  • 7刘杰,田志刚.新型白细胞介素简介[J].国外医学(肿瘤学分册),1997,24(3):158-160. 被引量:7
  • 8李杰,刘玉琴.MTT法在肿瘤研究中的改良及应用进展[J].中国肿瘤临床,1998,25(4):312-313. 被引量:69
  • 9许沈华,冯建国,李德川,牟瀚舟,楼荣灿.大肠癌患者外周血CD_(44)水平与临床病理的相关性研究[J].世界华人消化杂志,2000,8(4):432-435. 被引量:15
  • 10张彩,田志刚,王郡甫,刘金生,张建华,许晓群,孙江.人外周血NK细胞3种纯化方法的比较[J].中华微生物学和免疫学杂志,2000,20(1):83-84. 被引量:3

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同被引文献4

  • 1须珏华,胡静波,周燕,谭文松.培养基对兔骨髓间充质干细胞扩增与分化的影响[J].中国组织工程研究与临床康复,2007,11(3):467-470. 被引量:8
  • 2Chang DT, Colton E, Matsuda T, et al. Lymphocyte adhesion and interactions with biomaterial adherent macrophages and foreign body giant eells[J]. J Biomed Mater Res A,2009,91(4):1210.
  • 3Wei J,Satomi M, Negishi Y, et al. Effect of sera on the adhesion of natural killer cells to the endothelium in severe pre-eclampsia [J]. J Obstet Gynaecol Res,2006,32(5):443.
  • 4ChanCJ, Smyth MJ, Martinet L. Molecular mechanisms of natural killer cell activation in response to cellular stress[J]. Cell death and differentiation, 2013,21 (1): 5.

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