快速荧光素测定法在抗肿瘤药物筛选中的应用

Rapid Fluorescence Assay in Drug SensitvityTest of Human Tumor

快速荧光素测定法是一种近几年发展起来的、应用非常广泛的体外药物敏感性测定方法。本实验通过其在抗肿瘤药物筛选中的应用，对此方法进行了探讨和改进，使其更简便易行。实验结果表明，荧光素测定法具有线性好，测定范围宽的优点。此外，还具有快速、灵敏和重现性好的特点。适用于大量抗肿瘤药物的普筛和临床抗肿瘤药物的预试。

Rapid fluorescence assayls a method developed in recent yearsand widely applied in the determination of drug sensitivity in vitro.The autnorsmodified and simplified this method in human tumor and made it more practical.Itprovided good linear correlation, wide range of assay, high sensitivity and good reproducibility.It can be used in screening large number of antitumor drugs in vitro.