摘要
观察了44例老年消化系统肿瘤病人血浆,红细胞内微量元素会、硒与T细胞亚群间的变化。其结果显示:老年消化系统肿瘤病人与健康老年组相比,T细胞亚群水平低于对照组,并且肿瘤与健康组相比,前者随锌、硒比值下降的同时,T细胞亚群CD3、CD4及CD4/CD8比值均下降,而CD8增高,显示出免疫调节紊乱。这表明老年人缺锌、缺硒可引起机体免疫功能减退,而免疫功能减退则是引起消化系统肿瘤的危险因素。
Changes of trace elements zinc,selenium of plasma and RBC as well as T cell subsets in 44 cases of elder patients with digestive system tumour were observed and compared with 30 healthy elder people.The results showed that the levels of T cell subsets,the trace elements Zn and Se in plasma and RBC all were lower than those in controls.In patients with decreased Se,Zn and the T cell subsets,CD3 CD4,the ratio of CD4/CD8 also decreased but CD8 was increased.These results indicate that the lack of Zn and Se would cause deterioration of immune function,and predispose to development of digestive system tumour.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1996年第8期562-564,共3页
Chinese Journal of Clinical Oncology