Malignant phyllode tumor metastatic to the duodenum

Phyllode tumor （PT） is extremely rare tumor of the breast. Distant metastasis occurs in 10-20% of patients with malignant phyllode tumor. The most common sites of metastases are the lungs and bones. Although theoretically any organ may have metastasis, an isolated duodenum metastasis has not been documented as yet in the English-language literature. We report herein a case with a isolated duodenal metastasis from PT of breast in a 31 year-old-woman who underwent right mastectomy 4 years before because of the recurrent malignant PT. She presented to our hospital with massive upper gastrointestinal bleeding. Clinical evaluation revealed a huge mass originated from duodenum. Urgent laparotomy and pancreaticoduodenectomy were carried out in order to remove the bleeding duodenal mass. The pathologic examination of the resected specimen showed a malignant spindle cell tumor consistent with metastatic malignant PT. Our case of gastrointestinal bleeding due to an isolated duodenal metastasis as a result of hematogenous spread from malignant phyllode tumor of breast is unique in the English literature and pancreaticoduodenectomy is a curative treatment for patients with isolated duodenal involvement.

叶状叶柄肿瘤(磅) 是胸的极其稀罕的肿瘤。远转移与恶意的叶状叶柄肿瘤发生在病人的 10%-20% 。转移的最普通的地点是肺和骨头。尽管理论上任何机关可以有转移，孤立的十二指肠转移没在英语语言的文学迄今为止被记录。我们此处在 31 year-old-woman 从胸的磅与孤立的十二指肠的转移报导一个案例因为周期性的恶意的磅，以前恰好经历了乳房切除术 4 年。她介绍了给我们的医院与巨大上面的胃肠的流血。临床的评估表明一个巨大的团从十二指肠发源。迫切剖腹术和 pancreaticoduodenectomy 被执行以便移开流血十二指肠的质量。resected 标本的病理学的考试显示出与变形的恶意的磅一致的一个恶意的锭子房间肿瘤。我们从胸的恶意的叶状叶柄肿瘤的由于造血的传播的由于孤立的十二指肠的转移的胃肠的流血的案例在英语文学是唯一的， pancreaticoduodenectomy 是为有孤立的十二指肠的参与的病人的祛病疗法。