尿道下裂患者手术前后的尿道细菌分布

Bacteria study of urethra of preoperative and postoperative hypospadias cases

目的了解尿道下裂患者尿道修复前后尿道及其周围细菌的分布。方法用普通无菌棉拭子采集30例尿道下裂患者术前异位尿道和会阴部与术后重建尿道、会阴部皮肤样本,检测细菌分布。结果手术前后尿道与会阴部细菌分布基本一致,革兰阳性菌有表皮葡萄球菌、肠球菌等,革兰阴性菌有变形杆菌、阴沟肠杆菌、大肠杆菌等,以表皮葡萄球菌占多数。结论术后尿道内存在的细菌由会阴部表面细菌转移而来;菌株以革兰阳性菌表皮葡萄球菌占多数,菌株耐药率较高,临床选择药物要慎重。

Objective：The purpose of the study is to find out the bacteria distribution of the distal urethra and perineum of preoperative and postoperative hypospadias cases so as to prevent infection postoperatively. Methods： 30 samples from the distal urethra and perineum of preoperative and postoperative cases were collected respectively; the bacterial culture, identification was done. Results：The bacteria distribution of the distal urethra was almost the same as that of the perineum preoperatively and postoperatively. There were Gram-positive bacteria and Gramnegative bacteria, Gram-positive bacteria included Staphlococcus epidermidis,Enterococcus and so on, Gram-negative bacteria included P. mirabilis, E. cloacac,E, coil and so on. The majority of the bacteria was Staphlococcus epidermidis. Conclusions：Bacteria of the distal urethra might came from the perineum. Drug resistance rates of bacteria to antibacterials were high. Clinic doctors should be cautious to drug choice.