男性不育症患者精浆锌与血清生殖激素测定及意义

Clinical significance of sperm zinc and serum genital hormone detection in male infertility

目的评价精浆锌及血清生殖激素水平测定在不育症诊断及判定睾丸功能损害程度的意义。方法对200例男性不育症患者进行了精浆锌、血清生殖激素(FSH、LH、T、PRL)检测,并结合精液常规检查、睾丸容积测定以及睾丸病理活检进行分析。结果不育症患者精浆锌含量下降、血清生殖激素异常与睾丸间质细胞功能受损、生精上皮不同程度的破坏有明显的关系。结论精浆锌及血清生殖激素的检测,对判定男性不育症患者睾丸损害程度及鉴别睾丸原发性与梗阻性无精子症具有重要的作用。

Objective：To evaluate the significance of sperm zinc and serum genital hormone detection in male infertility. Methods;Sperm zinc, serum genital hormone（FSH, LH, T, PRL）, semen analysis were detected in 200 male infertile patients, in the meantime, testicle dimension measuration and testicle biopsy were done for all cases. Results： The abnormalities of sperm zinc and serum genital hormone content were related with testicle function damage. Conclusions：The detections of sperm zinc and serum genital hormone were significant for estimating testicle damage degree, also for distinguishing between primary and obstructive azoospermia.