对色素痣恶变几个问题的探讨

The Opinion about the Canceration of Melanocytic Nevi.

收集７０例有完整记录的ＭＭ临床及病理资料，对哪些色素痣易恶变？普通后天性痣（ＡＮ）是否易恶变以及组织病理对诊断色素痣恶变的意义等进行探讨。我们认为：１．色素痣恶变的诊断有赖于对病史的正确采集和分析，仅根据病理上有痣细胞的证据，尚不足以正确判断部分ＭＭ是否源于色素痣；２．除已获一致意见的先天性巨痣、发育不良性痣易恶变外，先天性小痣（ＣＳＮ）也易恶变；３．ＡＮ恶变尚缺乏确切资料。

Based on 67 cases of 70 malignant melanoma(MM) which had complete information clinical and histologic data acquired, some problems were discussed in this article.It was suggested that(1) most canceration of melanocytic nevi need depend on the correct collection and analysis of history,only dependent on the evidence of nevus cells on histology,is not enough to correctly judge a part of MM associated with melanocytic nevi whether originated from CSN or AN,(2)besides the congenital giant nevi and dysplastic nevi,CSN is easy to become malignant and (3) itis lacking of reliable evidence that MM originated from AN in literature,the data about canceration of AN need to study further.