小剂量纳洛酮治疗新生儿窒息34例临床体会

Cinical observation of low-dose naloxone on 34 cases of asphyxia of newborn

目的:观察小剂量纳洛酮治疗新生儿窒息的疗效。方法:64例新生儿窒息患儿随机分为治疗组34例和对照组30例,治疗组在对照组常规治疗的基础上加用纳洛酮0.01￣0.03mg/(kg.次)治疗。结果:治疗组显效率和总有效率均高于对照组,差异有统计学意义(P<0.05)。结论:小剂量纳洛酮治疗新生儿窒息疗效肯定,未见不良反应。

Objective： To investigate the chnical effects of the low-dose naloxone on asphyxia of newborn. Methods： 64 cases were divided into two groups randomly. Beside the routine therapy, treatment group were treated with naloxone at a dose of 0.01 - 0.03 mg/kg every time. Results： Total effective rate of treatment group was higher than that of control group （P 〈 0.05）. Conclusions： The low dose of naloxone has better efficacy and fewer side effects on asphyxia of newborn.