应用纳米羟基磷灰石/聚酰胺66复合人工椎体治疗脊椎结核

Application of nano-hydroapaic crystals and polymide compsite for artificial vertebrae in treating spinal tubrculosis.

目的探讨纳米羟基磷灰石/聚酰胺66(n-HA/PA66)复合人工椎体在脊柱结核中的应用价值。方法自2003年12月至2005年10月,对19例脊柱结核患者行胸腰椎前路病灶清除、椎管减压复合人工椎体植入、前路钉板内固定术。术后随访6~12个月。结果19例患者切口均一期愈合,无慢性窦道形成。术后6个月复合人工椎体植骨融合率达85%,无内固定松动及螺钉断裂。结论脊柱结核的治疗是病灶清除、减压矫形、植骨融合和坚强固定。复合人工椎体具有良好的生物相容性和生物安全性,植入融合率高,牢固可靠,避免了自体髂骨取骨,是理想的骨移植替代材料。

Objective To discuss the application of nano-hydroapatic crystals and polymide composite for artificial vertebrae in treating spinal tubercalusis.Methods A total of 19 cases suffering from thoracic or spinal tul^realusis were treated with deuto-total vertebrae resection via anterior approach, canalls vertebralis dcbcosted, artificial vertebrae composed by implanted and fixed with XIA screwstick system. The follow up lasted 6 - 12 months. Results All patients＇ incision healed without chronic infection and sinus formation. The rate of bone graft fusion reached 85 %, with no loosened internal fumtion or breakage of screw or stick. Conclusion Fusion and internal fixation were the keys for restoration of the stability of spinal column, solid fusion and correction of the kyphotic deformity. Artificial vertebrae is the ideal substitute material for bone trans-plantation, for it has good biocompatibility, high security, high rate of bone graft fusion and firm fixation.