帕歌斯治疗急性痛风性关节炎疗效观察

Clinical Observation on Pagosid in the Treatment of Acute Gouty Arthritis

目的:观察帕歌斯治疗急性痛风性关节炎临床疗效。方法:将70名患者随机分为治疗组(帕歌斯)与对照组(秋水仙碱),观察2组治疗起效时间及症状改善、血尿酸水平下降及对患者的不良反应情况。结果:2组均能改善急性痛风性关节炎临床症状,但治疗组可降低血尿酸水平,不良反应较小,起效时间较慢(65.78±30.19)h。结论:帕歌斯可改善高尿酸血症,减轻疼痛肿胀,用于治疗急性痛风性关节炎易为患者接受。

OBJECTIVE：To observe the therapeutic effect of pagosid in treating acute gouty arthritis.METHODS： 70 patients were randomly assigned to treatment with pagosid（treatment group） or colchicine（control group）, the onset time of therapeutic effect, symptom amelioration, blood uric acid descending level and adverse drug reactions of the two groups were monitored.RESULTS： There were ameliorated clinical symptoms in both groups; however, the blood uric acid level of the treatment group were redueed, and little adverse reaction involved in this group and the onset of curative effects was slow, which stood at（65.78±30.19） hours.CONCLUSION： Treatment of acute gouty arthritis with pagosid ameliorates hyperuriccmia and mitigates pain and swelling accepted by patients better.