方剂药效物质基础的复杂性特征及其研究思路

Adjust Study Thought Method According to Complexity Characteristics of Prescription Pharmacodynamic Material Bases

方剂药效物质系统和方剂与人体作用的的复杂性特征决定了应当在复杂性科学理论的指导下进行方剂药效物质基础的研究。根据复杂性科学的观点,方剂药效物质基础不是单味药有效成分或有效部位的药理作用,药效物质不一定局限于能被检测到的化学成分,药效物质系统不是方剂中所有单味药化学成分的总和。在中医药理论指导下,以整体观念为特色,以临床疗效为中心,用复杂科学的理论和思维方法进行研究更符合方剂本身的规律。

Both the prescription pharmaeodynamie material system and the interaction between the prescription and human body have eomplexity characteristics. The characteristics have decided that the study of prescription pharmacodynamic material - bases should be guided by the theory of complexity science. According to the viewpoint of complexity science, the prescription pharmacodynamic material bases is not the pharmacological action of the effective component or the effeetive spot of single Chinese herb, pharmacodynamie material do not only include the chemical composition that can be examined, pharmacodymamic material system is not the sum of all the chemical composition in the preparation. It conforms to the rules of the prescription if we study prescription pharmacodynamic material system instructing by the theory of Traditional Chinese Medicine and the theory of complexity - science, centering on the clinical curative effect, characterizing by the integral concept.