7种职业747例皮肤过敏性患者应用斑贴试验临床分析

Clinical analysis of applying patch test in 747 allergic patients with 7 various occupations

目的探讨不同职业皮肤过敏性疾病与外源性抗原的关系。方法7种不同职业747例过敏性患者行斑贴试验。结果办公室人员、学生、医师和护士4种职业斑试反应阳性率均占本行业斑试人数32%以上。在斑试反应中,办公室人员、教师、护士出现最多的抗原为芳香混合物,而机械工、营业员则为硫酸镍。结论各种职业之间,引起过敏反应的外源性抗原存在差异。

Objective To explore relation between allergic disorders and exogenous antigens among various occupations. Methods Patch test （PT） were performed in 747 allergic patients with 7 various occupations. Results Rates of positive PT were more than 32% patients of performing PT in office worker, student, doctor and nurse respectively. In positive PT, fragrant miture was the most antigen in office worker, teacher, nurse; while nickel sulfate was the most antigen in mechanic, shop employee. Conclusion Exogenous antigens are different in the induction of allergic response among various occupations.