K_2CO_3/CH_3COOK混合固体碱催化合成肉桂酸

Synthesis of Cinnamic Acid Using Solid Base as Catalyst

用K2CO3/CH3COOK混合固体碱催化苯甲醛-醋酐合成肉桂酸,用正交实验探讨了最佳合成条件.实验结果表明,最佳合成条件为:固体碱用量4.0 g,固体碱配比m(K2CO3):m(CH3COOK)=1:2,反应时间45 min.最佳合成条件下肉桂酸产率达76%.

Cirmamic acid was synthesized from benzaldehyde and acetic anhydride using solid base K2CO3 /CH3COOK as catalyst. Synthesis conditions were discussed in orthogonal experiment method. Results show that the optimum conditions of the reaction as follows： the amount of solid base is 4.0 g, the ratio of solid base is m（K2CO3）： m（CH3COOK）=1：2; reaction time is 45 min. Under optimal conditions, the yield of cinnamic acid is 76%.