85例儿童过敏性紫癜临床分析

Clinical analysis of 85 cases with Henoch-Schnlein purpura

目的分析小儿过敏性紫癜(HSP)的临床特点,提高临床诊治水平。方法对2003年1月至2005年1月在我科治疗的85例过敏性紫癜患儿的发病特点、临床表现、相关实验室检查等方面进行回顾性分析。结果(1)HSP主要发生于学龄前儿童和学龄儿童共84例,占98.82%。(2)诱因:感染62例,占72.94%,进食特殊食品8例,占9.41%。(3)出现肾脏损害者30例,发生率35.29%。(4)在64例做心电图检查者中出现心电图异常者23例,发生35.94%。(5)在35例心肌酶谱检查者中9例患儿一项或多项异常,发生率25.71%。结论(1)HSP发病诱因仍以感染为第一位。(2)多部位受累者发生肾脏受累和心电图改变。(3)单一器官的严重损害比多个器官的较轻损害对患儿预后影响更大。

Objective To study the clinical characteristics of Henoch-Schonlein purpura （HSP）. Methods The 85 cases with HSP treated from January, 2003 to January, 2005 were retrospectively studied and patterns of onset, clincal manifestations, correlated examine of laboratory were analysed. Results （ 1 ） of the 85 cases, 84 （98.82%） were preschool age and school age. （2） Inducing factors： The inducing factors were infections （62 cases, 72.94% ）, special food （8 cases, 9.41% ）. （3） Totally 30 cases （35.29%） presented symptoms of renal damage. （4） of the 64 cases,23 （35.94%） there were unusual electrocardiogam. （5） of the 35 cases, 9（25.71% ） there were one or more unusual myocardiac enzyme in the HSP patients. Conclusion （ 1 ） The most important inducing factor was infection. （2） Those with manay organ were afected tended to have renal damage and electrocardiogram change. （3） It is bigger effect on prognosis of HSP patients that one organ was grave damged than manay organ were light harmed.