摘要
基于Monod模型推导出了A.f的生长动力学方程模型,采用Gauss-Newton算法确定了在不同初始条件下细菌生长的动力学参数,即最大比生长速率μm、Monod常数K及R0。通过在不同初始条件下细菌生长特性的研究,得到了相应初始生长条件下以限制性底物亚铁离子浓度为表征的生长动力学方程,理论上揭示了动力学参数变化对细菌生长的影响规律,其中生长动力学方程的数值模拟与实验数据相吻合。
A kinetic model for growth of A. ferrooxidans was deduced on the basis of the Monod equation, the values of kinetic parameters (i.e. Monod constant K, maximum growth rateμm and R0) in different initial experiment conditions were calculated by using Gauss- Newton algorithm.Through the researching of the growth characteristics of under the conditions, the kinetic equation for growth of A. ferrooxidans, which was represented by restricted substrate ferrous ion concentration under the corresponding conditions, was obtained, which, theoretically, revealed the influence of the kinetic parameters on the growth ofA. ferrooxidans, and the numerical simulation in kinetic equation for growth of A. ferrooxidans was proved to be consistent with the experimental data.
出处
《现代生物医学进展》
CAS
2006年第2期5-8,共4页
Progress in Modern Biomedicine
基金
国家自然科学基金资助项目(No.50374075)
国家重点基础研究发展规划项目资助(973)
(No.2004CB619200)
关键词
嗜酸氧化亚铁硫杆茼
生长特性
动力学参数
生长动力学方程
数值解
Acidithiobacillus ferrooxidans
Kinetic model parameter
Growth behavior
Growth velocity equation
numerical solution