纵隔生殖细胞瘤临床分析

Clinical analysis of non-genitals mediastinal seminoma

目的:分析生殖器外纵隔生殖细胞瘤诊断和影响预后的因素。方法:65例纵隔生殖细胞瘤均行开胸手术治疗。单纯完全摘除肿瘤59例;姑息性切除1例;肿瘤摘除联合肺叶切除或胸膜纤维板剥脱术3例;开胸探查2例。恶性生殖细胞瘤术后均行辅助放、化疗。结果:良性畸胎类肿瘤手术摘除或合并肺、胸膜切除后效果良好。恶性生殖细胞瘤,尤其是精原细胞瘤切除后,辅助放、化疗仍可获得较好的远期生存。3年生存率66.7%。结论:纵隔生殖细胞瘤是常见的纵隔肿瘤,诊断后积极手术治疗可获得较好的结果。

OBJECTIVE.-To analyse ,clinical diagnosis and prognostical factors of non-genital mediastinal seminoma. METHODS： sixty-five patients with mediastinal seminomas were performed with open thoracic operation. Of 65 patients, 59 patients, were performed with umpleted resection, I patient with palliative resection, 3 patients with seminoma extracted and combined lobectomy or decortication and 2 patients with open thoracic exploration. All patients were administrated by adjuvant radiotherapy or/and chemotherapy after malignant seminomas resection. RESULTS： There were good results after benign teratoid tumor extrated or combined lobectomy or decortication. It was sure to get good survival after malignant seminoma, special germ cell tumor resection and assistant radiotherapy or/and chemotherapy 66.7% in 3y sicrvival. CONCLUSIONS： Mediastinal seminoma is a common mediastinal tumor. It is able to get better results when the seminoma resected actively after determining the diagnosis.