神经干细胞分化影响因素的研究进展
Advances in influence factors for differentiation of neural stem cells
摘要
神经干细胞(neuralstemcells,NSCs)在体外诱导条件下,可以分化成神经系统的三种主要细胞:神经元、星形胶质细胞、少突胶质细胞。移植入动物体内它也能分化成神经元和胶质细胞并能迁移到宿主中枢神经系统(CNS)的不同部位,与宿主细胞形成突触联系。其影响因素有外部因素和内在机制两个方面,文章对生长因子、细胞因子、局部微环境等外部因素和bHLH基因转录因子、Notch信号途径、DNA甲基化等内在机制对NSCs分化影响研究进展作一综述。
出处
《生物医学工程与临床》
CAS
2006年第2期113-116,共4页
Biomedical Engineering and Clinical Medicine
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