涎腺混合瘤包膜浸润组织核仁组成区嗜银蛋白的定量研究

Quantitative Analysis of AgNOR of Silivary Gland Mixed Tumor Tissue Infiltrating the Membrane

本文应用银染法对８例有包膜浸润而形态学上不能诊断为恶性的混合瘤的核仁组成区嗜银蛋白（ＡｇＮＯＲ）进行了定量分析，并与无包膜浸润的混合瘤及恶性混合瘤进行对照研究。结果显示，包膜浸润组织的ＡｇＮＯＲ颗粒数与其主体瘤无显著性差异（Ｐ＞０．０５），而与无浸润者及恶性混合瘤相比均有非常显著性差异（Ｐ＜０．０１），其颗粒数更接近于恶性混合瘤。作者认为，混合瘤的包膜浸润属潜在恶性行为。

Variation in the count of silver stained nucleolar organizer region assiociated proteins (AgNOR) were studied in paraffin sections of 8 salivary gland mixed tumors with membrane infiltrated, compared with no membrane in filtrating and malignant mixed tumors. There was no significant difference between the AgNOR counts in the cells infiltrating the membrane and cells of primary tumors (P>0.05), while there was significant difference in the cells of salivary gland with no membrane infiltrated mixed tumors, cells infiltrating the membrane and salivary gland malignant mixed tumors cells (P<0. 01). It wasconcluded that the membrane infiltration of the salivary gland with mixed tumor is a potential malignant phenomenon.