脑炎患儿血清游离钙离子浓度测定的临床意义

Investigation of serum ionized calcium in children with encephritis and its clinical significance

目的:研究脑炎患儿血清游离钙浓度测定的临床意义。方法:采用离子交换电极法,测定20例呼吸道感染患儿(1组)、15例呼吸道感染并热性惊厥患儿(2组)、20例脑炎(3组)患儿血清的游离钙离子浓度,将所测值进行统计学处理。结果:3组患儿血清游离钙浓度平均值分别是(1.2890±0.0408)mm o l/L、(1.2627±0.1311)mm o l/L、(1.1655±0.0958)mm o l/L,各组间q检验示:1组与2组q=1.1765,P>0.05;1组与3组q=5.9599,P<0.01;2组与3组q=4.3413,P<0.01。结论:血清游离钙离子浓度的测定,间接反映了脑水肿的发生和严重程度。

Objective： To investigate serum ionized calcium （[Ca^2＋]i） in children with encephritis and its clinical significance. Methods： Serum ionized calcium in 20 children with respiratory infection（group 1）, 15 children with respiratory infection combined with febril convulsion （group 2） and 20 children with encephritis （group 3） were measured respectively by the electrode way of ion exchange. Results： The average levels of [Ca^2＋]i of these three groups were （1.2890±0.0408）mmol/L, （1.2627±0.1311）mmol/L and （1.1655±0.0958）mmol/L, respectively. There wasn＇t obviously difference between the group 1 and group 2 （q = 1.1765, P 〉 0.05）. Compared with group 1 and 2, the level of [Ca^2＋]i in group 3 was decreased remarkably （q were 5.9599 and 4.3413 respectively. P〈0.01 both）. Conclusion： The decrease of [Ca^2＋]i has relationships to brain edema and its serious degree.