性分化与性发育异常13例分析

Clinical Analysis of 13 Cases of Sex Disdifferentiation and Dysplasia

目的：探讨性分化和发育异常的临床特点，并对腹腔镜在治疗中的应用进行评价。方法：对我院13例行腹腔镜切除性腺的性分化和发育异常病例资料进行分析。结果：13例均为女性外阴，含有Y染色体或Y的成分，性腺位于腹腔内或腹股沟内，4例为条索状原始性腺，9例为睾丸。3例有始基子宫和输卵管。性激素水平符合绝经期表现。11例经腹腔镜完成手术，2例转传统手术，手术后1～2天出院。结论：含有Y染色体或Y成分的性腺位于腹腔或腹股沟内并且丧失正常功能，是手术切除的指征，腹腔镜手术具有微创和术后恢复快的优势。

Objective： To discuss the clinical features of sex disdifferentiation and dyaplasia as well as to evaluate the application of laparoscopy in treatment. Methods： 13 cases of sex disdifferentiation and dysplasia undergone laparoscopy were collected and analyszed. Results： The vulva of 13 patients was of female features. Y chromosomes or the chromosome containing Y ingredient have been detected. The gonads were either in abdomen or in inguinal canals, 4 pairs taking the shape of cord and 9 pairs taking the shape of testis. 3 primitive uteri were found with oviducts. Sex hormones were in accordance with menopausal features. Laparoscopy were smoothly performed in 11 cases and converted to conventional operation in the other 2 cases. The discharge was 1～2 days later. Conclusions： Indication for gonadectomy includes Y chromosome or chromosome containing Y ingredient and dysfunctioning of the malpositiened gonads. Laparoscopy is dominated in microinvasion and quick recovery.