0.13%百瓒防蛀气雾剂毒理学研究

Toxicological study of 0.13% Baizan aerosol for prevent moth

对0.13%百瓒防蛀气雾剂及其主要有效成分辛硫磷进行了毒理学研究。结果表明:急性吸入毒性(LC50):雌、雄小鼠均大于2150mg/m3;急性经口毒性(LD50):小鼠为9 210mg/kg;皮肤刺激实验:无刺激作用;皮肤变态反应:致敏率为“0”;眼刺激试验:无刺激性;辛硫磷原药(85%)对大鼠28d亚急性吸入毒性:对雄、雌性大鼠无作用浓度(NOAEL)均为10mg/m3。

0. 13 % Baizan aerosol for prevent moth and phoxim, its main effective component were evaluated by toxicological study. The acute inhale test（LC50）, the acute peroral toxicity text（LD50 ）, the skin stimulate text, the in allergy reaction and the eye stimulate text had been done with 0.13 % Baizan aerosol for prevent moth. The main effective component, phoxim were done the acute inhale toxicity text with mice for 28d.The results showed that acute inhale toxicity（LDso ） for male and female mice was more than 2 150mg/ms ,acute peroral toxicity（ LD50 ） was 9 210mg/kg, The skin and eye stinmlate text and the skin allergy reaction was all negative, the no-reaction concertration of 85% phoxim to male and female rats for 28d was 10mg/m^3.