某学院新生HBsAg,ALT与乙型肝炎病毒疫苗接种情况分析

Analysis on HBsAg,alanine transaminase and hepatitis B vaccination in new students in a college

目的了解某学院入学新生乙型肝炎(乙肝)表面抗原(HBsAg)携带和丙氨酸转氨酶(ALT)异常及乙肝疫苗接种情况,为高校医疗保健和预防工作提供依据。方法采用现况调查,对1999-2001年入学新生进行HBsAg和ALT检测,并询问有无乙肝疫苗接种史。结果3年共检测2 789名新生,HBsAg阳性者243人,阳性率为8.71%。城镇新生HBsAg阳性率为7.64%,农村新生为9.11%,两者比较,差异无显著性(P>0.05);男性新生HBsAg阳性率为9.65%,女性新生为7.25%,两者比较,差异有显著性(P<0.05)。3届新生乙肝疫苗接种率为21.40%,其中城镇新生接种率为25.03%,农村新生接种率为20.05%,两者比较,差异有显著性(P<0.05)。ALT异常率为5.88%。结论高校新生入学时检测HBsAg和ALT,了解乙肝疫苗接种覆盖率,对做好大学生乙肝防治和医疗保健工作具有重要意义。

Objective To realize the carriage of HBsAg and abnormal alanine transaminase （ALT） and hepatitis B vaccination in new students in a college, so as to provide evidence of medical care for the college students. Methods HBsAg and ALT were detected in new students, and hepatitis B vaccination history was inquired. Results 2 789 new students were detected within three years, 243 （8.71% ） students were HBsAg positive. The HBsAg positive rate in new students from city and rural area was 7.64% and 9.11% respectively, there was no obvious difference between the two （ P 〉0.05） ; HBsAg positive rate in male and female students was 9.65% and 7.25% respectively, there was significant difference between the two （ P 〈0.05）, hepatitis B vaccination rate in these students was 21.40%, the vaccination rate in students from city and rural area was 25.03% and 20.05% respectively, there was significant difference between the two （ P 〈 0.05）. The abnormal rate of ALT was 5.88 %. Conclusion The detection of HBsAg and ALT and investigation on the hepatitis B vaccination rate in new college students is significant for the prevention of hepatitis B and helpful for the medical care.