糖尿病医院感染患者糖化血红蛋白的监测意义

Significance of detection on glycosylated hemoglobin in nosocomial infection patients with diabetes mellitus

目的探讨糖化血红蛋白值监测对糖尿病患者发生医院感染评估的临床意义。方法检测61例糖尿病医院感染患者(感染组)与61例糖尿病未发生医院感染患者(对照组)的糖化血红蛋白值与空腹血糖值,并进行统计分析。结果感染组糖化血红蛋白值为(9.68±2.38)%,空腹血糖值为(9.65±2.89)mmol/L;对照组糖化血红蛋白值为(6.35±2.07)%,空腹血糖值为(8.98±2.64)mmol/L;两组糖化血红蛋白值比较,差异有显著性(P<0.01),空腹血糖值差异无显著性(P>0.05)。结论糖化血红蛋白值可作为糖尿病患者医院感染高危因素的监测指标之一,其稳定性优于空腹血糖值。

Objective To evaluate the clinical significance of detection on glycosylated hemoglobin （GHb） in nosocomial infection （NI） patients with diabetes mellitus （DM）. Methods GHb and fasting blood-glucose level in 61 DM patients with NI （infective group） and 61 DM patients without NI （control group） were detected and analysed statistically. Results GHb and fasting blcod-glucose level in infective group was （9.68 ± 2.38） % and （9.65 ± 2.89） mmol/ L respectively; Glib and fasting blood-glucose level in control group was （6.35 ± 2.07）% and （8.98 ± 2.64） mmol/L respectively, there was significant difference in the Glib level between two groups （ P 〈 0.01）, but there was no significant difference in the fasting blcod-glucose level between two groups （ P 〉0.05）. Conclusion GHb level can be valued as one of the risk factors for the occurrencee of NI in patients with DM, its stability is superior to the fasting blood-glucose level.