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重症肌无力患者病情和补体浓度之间的相关性 被引量:2

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摘要 目的检测治疗前、后重症肌无力(Myasthen ia gravis,MG)患者血清中补体浓度的变化,探讨补体浓度和MG患者病情之间的相关性。方法对MG患者进行糖皮质激素规范化治疗,检测患者治疗前、后血清补体浓度,并计算治疗前、后患者补体浓度的差值,同时对MG患者进行病情定量评分,计算治疗后的相对评分。结果C3浓度MG组治疗前明显低于非MG对照组(NC组)(P<0.01),治疗后浓度增高(P<0.01),但仍低于NC组;C5浓度治疗前、后2组差别不显著(P>0.05);双变量回归相关分析补体的浓度与病情相关性不显著。结论经过治疗MG患者病情好转血清C3浓度增高,C5浓度变化不明显,病情变化与补体的浓度变化的相关性不显著。
出处 《卒中与神经疾病》 2006年第2期122-124,共3页 Stroke and Nervous Diseases
基金 国家自然科学基金资助项目(编号30270455)
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