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Ki67在卵巢癌中的表达及临床意义 被引量:9

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摘要 采用免疫组织化学SP法检测Ki67在20例卵巢良性肿瘤、10例交界性肿瘤、42例卵巢癌中的表达,并分析它们与卵巢临床病理指标的关系。结果:卵巢良性肿瘤KI指数为2.00±1.22,交界肿瘤为10.20±5.03,卵巢癌为35.20±15.20,三组比较,差异显著(P〈0.01);Ⅲ~Ⅳ期卵巢癌KI指数为35.75±12.30,显著高于Ⅰ~Ⅱ期卵巢癌的22.00±11.20(P〈0.01);中低分化癌KI指数为34.17±9.08,显著高于高分化癌的22.88±10.02(P〈0.01);卵巢癌Ki指数与组织类型、淋巴转移无关(P〉0.05)。结果表明,卵巢癌中Ki67表达显著高于卵巢良性交界肿瘤。可作为鉴别良恶性肿瘤的指标;其表达与卵巢癌的临床分期、病理分级有关。
出处 《苏州大学学报(医学版)》 CAS 北大核心 2006年第2期321-321,323,共2页 Suzhou University Journal of Medical Science
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