垂体后叶素对肝硬化门脉高压血液动力学影响

Effects of Pituitrin on Portal Hemodynamies in Liver Cirrhosis With Portal Hypertension

本文报告10例肝硬化门脉高压患者静脉滴注垂体后叶素,每分钟0.1～0.2单位,同时应用超声脉冲多普勒测定与比较用药前后门脉流速和流量的变化。用药后门脉平均流速降低49.2％～50.6％,高峰流速降低42.0％～43.5％,流量降低40.8％～43.0％。这项非创伤性的检测方法,为临床选择垂体后叶素治疗门脉高压提供了客观指标。

The changes of portal venous velocity and flow in 10 patients with portal hypertension were measured by ultrasonic puised-Dopplex techniques before and immediately after intravenous infusion of pituitrin (0.1～0.2u/min). the mean portal velocity(49.2％～50.6％), peak velocityb(42.0％～43.5％) and portal flow (40.8％～43.0％) were decreased significantly in patients received the infusion of pituitrin. Thy Dopplex technique provides feasible method for the decision of pituitrin treatment in portal hypertension.