胸水及血清中ET,FN,CEA联合检测对良恶性胸水的鉴别诊断

Differentiation Diagnosis Value for Comnined Measuring of ET,FN,CEA in Hydrothorax and Serum in Benign and Malignant Hydrothorax

目的探讨胸水及血清ET(内皮素)、FN(纤维连接蛋白)、CEA(癌胚抗原)ET,FN,CEA联合检测对良恶性胸水的鉴别诊断价值。方法应用放免法、ELISA、免放法分别检测胸水及血清中的ET,FN,CEA。分别进行胸水及血清中ET,FN,CEA含量比较以及三项指标联合检测与单项指标的比较。结果诊断恶性胸水,单项指标检测中ET敏感性最高、CEA特异性最高,三者联合检测的敏感性、特异性、准确率均最高。结论胸水及血清ET,FN,CEA联合检测有助于提高良恶性胸水的诊断正确率。

Objective To probe the differentiation diagnosis value for combined measuring of serum and hydrothorax ET, FN, CEA in benign and malignant hydrothorax. Methods It was measured the ET, FN and CEA in hydrothorax and serum hy radiation immunity, ELISA and immunity radiation method respectively. And respectively compared the amount of ET, FN, CEA in hydrnthorax and surum. Results For diagnosis malignant hydrothorax, ET had the highest sensitivity and CEA had the highest specificity in single index,but comnined determination of ET, FN, CEA had the highest sensitivity, specificity and accuracy.Conclusion Comnined determination of ET,FN,CEA can improve the differentiation diagnosis of benign and malignant hydrothorax.