导致消化性溃疡出血患者进一步出血及死亡因素分析

Clinical Factors in the Prediction of Further Hemorrhage and Mortality After Peptic Ulcer Bleeding

分析了216例消化性溃疡出血患者进一步出血及死亡的原因,发现合并有心血管、肝脏疾病及恶性肿瘤的患者易发生进一步出血,合并存在有心血管、肝、肺、肾、神经内分泌疾病及恶性肿瘤的患者易发生死亡.患者第一个48小时需输血量超过4个单位者容易发生进一步出血及死亡.嗜酒、应用类固醇、住院治疗期间发生出血及进一步出血的患者易发生死亡.

The causes of further hemorrhage or death in 216 paiienls with bleeding peptic ulcer were investigated. We found that coexiting hepatic, cardiovascular diseases and malignant tumor was related to further hemorrhage- and coexiting system diseases are significant factors strongly related to mortality rate. A transfusion requirement of more than four units of blood during the first 48 hours was a significant factor thai predicted further hemorrhage and death. Other factors indicative of an increased mortality rate included steroid drug use, onset of bleeding during the peroid of hospitalization, alcohol use and further bleeding.