幽门螺杆菌感染机体相关细胞因子的研究

Study on the Correlative Cell Factors of Organism Were Infected by Helicobacter Pylori

幽门螺杆菌是一种胃和十二指肠疾病的重要致病因素,它感染机体后定植于人胃粘膜引起炎症反应,从而影响机体免疫反应,特别是单核巨噬细胞、T细胞、B细胞的免疫应答,导致其分泌的细胞因子失衡,如IL-1β、IL-2、IL-8、IFN-γ等。文章主要叙述了幽门螺杆菌感染机体后相关细胞因子在致炎和抑炎中的作用及中药对相关细胞因子的影响。

The helicobacter pylori was an important etiological factor for falling disease of stomach and duodenum. After being infected by it, it would plant in gastric mucosa and cause inflammatory reaction, consequently, the immune reaction of body was affected, especially the immune response of mononuclear macrophage, T cell and B cell lead to lose balance of cell factors secreted by it, for instance, IL - 1β, IL - 2, IL - 8, IFN - γ, et al. The paper expounded the cell factors＇ effect to cause or restrain inflammatory after idected by hellcobacter pylori and the effect of Chinese crude drugs on relative cell factors.